Mitochondrial Dysfunction in Skeletal Muscle of Amyloid Precursor Protein-overexpressing Mice

Inclusion body myositis, the most common muscle disorder in the elderly, is partly characterized by abnormal expression of amyloid precursor protein (APP) and intracellular accumulation of its proteolytic fragments collectively known as β-amyloid. The present study examined the effects of β-amyloid...

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Hlavní autoři: Boncompagni, Simona, Moussa, Charbel E.-H., Levy, Ezra, Pezone, Matthew J., Lopez, José R., Protasi, Feliciano, Shtifman, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2012
Témata:
Molecular Bases of Disease
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370238/
https://ncbi.nlm.nih.gov/pubmed/22518836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359588
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