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Mitochondrial Dysfunction in Skeletal Muscle of Amyloid Precursor Protein-overexpressing Mice

Inclusion body myositis, the most common muscle disorder in the elderly, is partly characterized by abnormal expression of amyloid precursor protein (APP) and intracellular accumulation of its proteolytic fragments collectively known as β-amyloid. The present study examined the effects of β-amyloid...

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Detalhes bibliográficos
Main Authors: Boncompagni, Simona, Moussa, Charbel E.-H., Levy, Ezra, Pezone, Matthew J., Lopez, José R., Protasi, Feliciano, Shtifman, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370238/
https://ncbi.nlm.nih.gov/pubmed/22518836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359588
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