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Loss of Mitofusin 2 Promotes Endoplasmic Reticulum Stress
The outer mitochondrial membrane GTPase mitofusin 2 (Mfn2) is known to regulate endoplasmic reticulum (ER) shape in addition to its mitochondrial fusion effects. However, its role in ER stress is unknown. We report here that induction of ER stress with either thapsigargin or tunicamycin in mouse emb...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370214/ https://ncbi.nlm.nih.gov/pubmed/22511781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359174 |
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