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Loss of Mitofusin 2 Promotes Endoplasmic Reticulum Stress

The outer mitochondrial membrane GTPase mitofusin 2 (Mfn2) is known to regulate endoplasmic reticulum (ER) shape in addition to its mitochondrial fusion effects. However, its role in ER stress is unknown. We report here that induction of ER stress with either thapsigargin or tunicamycin in mouse emb...

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Bibliografische gegevens
Hoofdauteurs: Ngoh, Gladys A., Papanicolaou, Kyriakos N., Walsh, Kenneth
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370214/
https://ncbi.nlm.nih.gov/pubmed/22511781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.359174
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