Highly Sensitive Quenched Fluorescent Substrate of Legionella Major Secretory Protein (Msp) Based on Its Structural Analysis

Legionella pneumophila has been shown to secrete a protease termed major secretory protein (Msp). This protease belongs to the M4 family of metalloproteases and shares 62.9% sequence similarity with pseudolysin (EC 3.4.24.26). With the aim of developing a specific enzymatic assay for the detection a...

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Bibliografiske detaljer
Main Authors: Poras, Hervé, Duquesnoy, Sophie, Dange, Emilie, Pinon, Anthony, Vialette, Michèle, Fournié-Zaluski, Marie-Claude, Ouimet, Tanja
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2012
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370204/
https://ncbi.nlm.nih.gov/pubmed/22528499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.334334
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