Dynamics and Distribution of Klothoβ (KLB) and Fibroblast Growth Factor Receptor-1 (FGFR1) in Living Cells Reveal the Fibroblast Growth Factor-21 (FGF21)-induced Receptor Complex

FGF21 stimulates FGFR1c activity in cells that co-express Klothoβ (KLB); however, relatively little is known about the interaction of these receptors at the plasma membrane. We measured the dynamics and distribution of fluorescent protein-tagged KLB and FGFR1c in living cells using fluorescence reco...

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Autores principales: Ming, Aaron Y. K., Yoo, Eunjong, Vorontsov, Eugene N., Altamentova, Svetlana M., Kilkenny, Dawn M., Rocheleau, Jonathan V.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2012
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370183/
https://ncbi.nlm.nih.gov/pubmed/22523080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.325670
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