טוען...
Augmented interleukin (IL) -15Rα expression by CD40 activation is critical in synergistic CD8 T-cell mediated antitumor activity of anti-CD40 antibody with IL-15 in TRAMP-C2 tumors in mice
Interleukin-15 (IL-15) has potential as an immunotherapeutic agent for cancer treatment because it is a critical factor for the proliferation and activation of natural killer (NK) and CD8(+) T cells. However, monotherapy of patients with malignancy with IL-15 that has been initiated may not be optim...
שמור ב:
| Main Authors: | , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2012
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370156/ https://ncbi.nlm.nih.gov/pubmed/22593619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102604 |
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