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Amino-Terminal Extended Peptide Single-Chain Trimers are Potent Synthetic Agonists for Memory Human CD8+ T cells
Upon antigen exposure, most memory T cells undergo re-stimulation induced cell death. Here we describe a novel synthetic agonist, an amino-terminal extended decamer peptide expressed as a single chain trimer, the AT-SCT, that preferentially promotes the growth of memory human CD8+ T cells with minim...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3370155/ https://ncbi.nlm.nih.gov/pubmed/22573808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103647 |
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