The mucin MUC16 (CA125) binds to NK cells and monocytes from peripheral blood of women with healthy pregnancy and preeclampsia

PROBLEM: MUC16 (CA125) released from ovarian tumors binds to NK cells and monocytes via the inhibitory receptor Siglec-9. Here, we investigate if MUC16 also binds to circulating immune cells during pregnancy and in women with preeclampsia. METHOD OF STUDY: MUC16 binding was monitored by flow cytomet...

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Bibliographic Details
Main Authors: Tyler, Chanel, Kapur, Arvinder, Felder, Mildred, Belisle, Jennifer A., Trautman, Christine, Gubbels, Jennifer A.A., Connor, Joseph P., Patankar, Manish S.
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370110/
https://ncbi.nlm.nih.gov/pubmed/22380506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0897.2012.01113.x
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