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Disruption of the Epithelial Apical-Junctional Complex by Helicobacter pylori CagA

Helicobacter pylori translocates the protein CagA into gastric epithelial cells and has been linked to peptic ulcer disease and gastric carcinoma. We show that injected CagA associates with the epithelial tight-junction scaffolding protein ZO-1 and the transmembrane protein junctional adhesion molec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Amieva, Manuel R., Vogelmann, Roger, Covacci, Antonello, Tompkins, Lucy S., Nelson, W. James, Falkow, Stanley
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369828/
https://ncbi.nlm.nih.gov/pubmed/12775840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1081919
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