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Disruption of the Epithelial Apical-Junctional Complex by Helicobacter pylori CagA
Helicobacter pylori translocates the protein CagA into gastric epithelial cells and has been linked to peptic ulcer disease and gastric carcinoma. We show that injected CagA associates with the epithelial tight-junction scaffolding protein ZO-1 and the transmembrane protein junctional adhesion molec...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369828/ https://ncbi.nlm.nih.gov/pubmed/12775840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1081919 |
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