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Disruption of the Epithelial Apical-Junctional Complex by Helicobacter pylori CagA

Helicobacter pylori translocates the protein CagA into gastric epithelial cells and has been linked to peptic ulcer disease and gastric carcinoma. We show that injected CagA associates with the epithelial tight-junction scaffolding protein ZO-1 and the transmembrane protein junctional adhesion molec...

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Detalhes bibliográficos
Main Authors: Amieva, Manuel R., Vogelmann, Roger, Covacci, Antonello, Tompkins, Lucy S., Nelson, W. James, Falkow, Stanley
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369828/
https://ncbi.nlm.nih.gov/pubmed/12775840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1081919
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