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Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells

CagA is a bacterial effector protein of Helicobacter pylori that is translocated via a type IV secretion system into gastric epithelial cells. We previously described that H. pylori require CagA to disrupt the organization and assembly of apical junctions in polarized epithelial cells. In this study...

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Main Authors: Bagnoli, Fabio, Buti, Ludovico, Tompkins, Lucy, Covacci, Antonello, Amieva, Manuel R.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1274241/
https://ncbi.nlm.nih.gov/pubmed/16258069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502598102
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