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DNA fragments binding CTCF in vitro and in vivo are capable of blocking enhancer activity
BACKGROUND: Earlier we identified ten 100-300-bp long CTCF-binding DNA fragments selected earlier from a 1-Mb human chromosome 19 region. Here the positive-negative selection technique was used to check the ability of CTCF-binding human genomic fragments to block enhancer-promoter interaction when i...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369819/ https://ncbi.nlm.nih.gov/pubmed/22480385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-0500-5-178 |
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