HTLV-1 CTCF-binding site is dispensable for in vitro immortalization and persistent infection in vivo

BACKGROUND: Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATL) and the neurological disorder HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). The exact mechanism(s) through which latency and disease progression are regulated...

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Detalhes bibliográficos
Publicado no:Retrovirology
Main Authors: Martinez, Michael P., Cheng, Xiaogang, Joseph, Ancy, Al-Saleem, Jacob, Panfil, Amanda R., Palettas, Marilly, Dirksen, Wessel P., Ratner, Lee, Green, Patrick L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6925871/
https://ncbi.nlm.nih.gov/pubmed/31864373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-019-0507-9
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