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HTLV-1 Rex is required for viral spread and persistence in vivo but is dispensable for cellular immortalization in vitro

Human T-cell leukemia virus type 1 (HTLV-1) is associated with leukemia/lymphoma and neurologic disorders. Although the viral transcriptional activator Tax is the critical viral oncoprotein, Rex, which regulates the expression of the viral structural and enzymatic genes, is essential for efficient v...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ye, Jianxin, Silverman, Lee, Lairmore, Michael D., Green, Patrick L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852248/
https://ncbi.nlm.nih.gov/pubmed/12907436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-05-1490
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