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HTLV-1 Rex is required for viral spread and persistence in vivo but is dispensable for cellular immortalization in vitro
Human T-cell leukemia virus type 1 (HTLV-1) is associated with leukemia/lymphoma and neurologic disorders. Although the viral transcriptional activator Tax is the critical viral oncoprotein, Rex, which regulates the expression of the viral structural and enzymatic genes, is essential for efficient v...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2852248/ https://ncbi.nlm.nih.gov/pubmed/12907436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-05-1490 |
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