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HTLV-1 Rex is required for viral spread and persistence in vivo but is dispensable for cellular immortalization in vitro

Human T-cell leukemia virus type 1 (HTLV-1) is associated with leukemia/lymphoma and neurologic disorders. Although the viral transcriptional activator Tax is the critical viral oncoprotein, Rex, which regulates the expression of the viral structural and enzymatic genes, is essential for efficient v...

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Bibliografske podrobnosti
Main Authors: Ye, Jianxin, Silverman, Lee, Lairmore, Michael D., Green, Patrick L.
Format: Artigo
Jezik:Inglês
Izdano: 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2852248/
https://ncbi.nlm.nih.gov/pubmed/12907436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2003-05-1490
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