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Y95 and E444 Interaction Required for High-Affinity S-Citalopram Binding in the Human Serotonin Transporter
[Image: see text] The human serotonin (5-hydroxytryptamine, 5-HT) transporter (hSERT) is responsible for the reuptake of 5-HT following synaptic release, as well as for import of the biogenic amine into several non-5-HT synthesizing cells including platelets. The antidepressant citalopram blocks SER...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Chemical Society
2010
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369724/ https://ncbi.nlm.nih.gov/pubmed/22778858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100066p |
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