“Clicked” Sugar–Curcumin Conjugate: Modulator of Amyloid-β and Tau Peptide Aggregation at Ultralow Concentrations

[Image: see text] The synthesis of a water/plasma soluble, noncytotoxic, “clicked” sugar-derivative of curcumin with amplified bioefficacy in modulating amyloid-β and tau peptide aggregation is presented. Curcumin inhibits amyloid-β and tau peptide aggregation at micromolar concentrations; the sugar...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Dolai, Sukanta, Shi, Wei, Corbo, Christopher, Sun, Chong, Averick, Saadyah, Obeysekera, Dinali, Farid, Mina, Alonso, Alejandra, Banerjee, Probal, Raja, Krishnaswami
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2011
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369720/
https://ncbi.nlm.nih.gov/pubmed/22860163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200088r
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares