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“Clicked” Sugar–Curcumin Conjugate: Modulator of Amyloid-β and Tau Peptide Aggregation at Ultralow Concentrations
[Image: see text] The synthesis of a water/plasma soluble, noncytotoxic, “clicked” sugar-derivative of curcumin with amplified bioefficacy in modulating amyloid-β and tau peptide aggregation is presented. Curcumin inhibits amyloid-β and tau peptide aggregation at micromolar concentrations; the sugar...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Chemical
Society
2011
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| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369720/ https://ncbi.nlm.nih.gov/pubmed/22860163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200088r |
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