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Targeted alterations in yeast artificial chromosomes for inter-species gene transfer.

In order to facilitate alterations of large DNA molecules for their introduction into mammalian cells we have characterised the mechanism of site-specific modifications in yeast artificial chromosomes (YACs). Newly developed yeast integration vectors with dominant selectable marker genes allow targe...

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Publicat a:Nucleic Acids Res
Autors principals: Davies, N P, Rosewell, I R, Brüggemann, M
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1992
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336909/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1614855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.11.2693
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