Targeted alterations in yeast artificial chromosomes for inter-species gene transfer.

In order to facilitate alterations of large DNA molecules for their introduction into mammalian cells we have characterised the mechanism of site-specific modifications in yeast artificial chromosomes (YACs). Newly developed yeast integration vectors with dominant selectable marker genes allow targe...

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Bibliographic Details

Published in:	Nucleic Acids Res
Main Authors:	Davies, N P, Rosewell, I R, Brüggemann, M
Format:	Artigo
Language:	Inglês
Published:	Oxford University Press 1992
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336909/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1614855/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.11.2693
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