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Improving Pedigree-based Linkage Analysis by Estimating Coancestry Among Families
We present a method for improving the power of linkage analysis by detecting chromosome segments shared identical by descent (IBD) by individuals not known to be related. Existing Markov chain Monte Carlo methods sample descent patterns on pedigrees conditional on observed marker data. These pattern...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368982/ https://ncbi.nlm.nih.gov/pubmed/22499699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2202/1544-6115.1718 |
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