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Computationally efficient multipoint linkage analysis on extended pedigrees for trait models with two contributing major loci

We have developed a computationally efficient method for multipoint linkage analysis on extended pedigrees for trait models having a two-locus QTL effect. The method has been implemented in the program, hg(-)lod, which uses MCMC method to sample realizations of descent patterns conditional on marker...

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Detalhes bibliográficos
Main Authors: Su, Ming, Thompson, Elizabeth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868922/
https://ncbi.nlm.nih.gov/pubmed/22740194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21653
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