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Osteoclast Activated FoxP3(+) CD8(+) T-Cells Suppress Bone Resorption in vitro
BACKGROUND: Osteoclasts are the body’s sole bone resorbing cells. Cytokines produced by pro-inflammatory effector T-cells (T(EFF)) increase bone resorption by osteoclasts. Prolonged exposure to the T(EFF) produced cytokines leads to bone erosion diseases such as osteoporosis and rheumatoid arthritis...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368916/ https://ncbi.nlm.nih.gov/pubmed/22701612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038199 |
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