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Structure and functional characterization of the RNA-binding element of the NLRX1 innate immune modulator

Mitochondrial NLRX1 is a member of the family of nucleotide-binding domain and leucine-rich-repeat–containing proteins (NLRs) that mediate host innate immunity as intracellular surveillance sensors against common molecular patterns of invading pathogens. NLRX1 functions in antiviral immunity, but th...

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Hlavní autoři: Hong, Minsun, Yoon, Sung-il, Wilson, Ian A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368889/
https://ncbi.nlm.nih.gov/pubmed/22386589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.12.018
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