Jacaranone Induces Apoptosis in Melanoma Cells via ROS-Mediated Downregulation of Akt and p38 MAPK Activation and Displays Antitumor Activity In Vivo

BACKGROUND: Malignant melanoma is a deadly type of metastatic skin cancer with increased incidence over the past 30 years. Despite the advanced knowledge on the biology, immunobiology and molecular genetics of melanoma, the alternatives of treatment are limited with poor prognosis. On clinical trial...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Massaoka, Mariana H., Matsuo, Alisson L., Figueiredo, Carlos R., Farias, Camyla F., Girola, Natália, Arruda, Denise C., Scutti, Jorge A. B., Romoff, Paulete, Favero, Oriana A., Ferreira, Marcelo J. P., Lago, João H. G., Travassos, Luiz R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368838/
https://ncbi.nlm.nih.gov/pubmed/22701695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038698
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