Early tumor progression associated with enhanced EGFR signaling with bortezomib, cetuximab, and radiotherapy for head and neck cancer

PURPOSE: A phase I clinical trial and molecular correlative studies were performed to evaluate preclinical evidence for combinatorial activity of proteasome inhibitor bortezomib, epidermal growth factor receptor (EGFR) inhibitor cetuximab, and radiation therapy. EXPERIMENTAL DESIGN: Patients with ra...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Argiris, Athanassios, Duffy, Austin G., Kummar, Shivaani, Simone, Nicole L., Arai, Yoshio, Kim, Seungwon W., Rudy, Susan. F., Kannabiran, Vishnu. R., Yang, Xinping, Jang, Minyoung, Chen, Zhong, Suksta, Nanette, Cooley-Zgela, Theresa, Ramanand, Susmita G., Ahsan, Aarif, Nyati, Mukesh. K., Wright, John J., Van Waes, Carter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368806/
https://ncbi.nlm.nih.gov/pubmed/21750205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0861
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge