Origin of myofibroblasts in liver fibrosis

Most chronic liver diseases of all etiologies result in progressive liver fibrosis. Myofibroblasts produce the extracellular matrix, including type I collagen, which constitutes the fibrous scar in liver fibrosis. Normal liver has little type I collagen and no detectable myofibroblasts, but myofibro...

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Bibliographic Details
Main Authors: Brenner, David A, Kisseleva, Tatiana, Scholten, David, Paik, Yong Han, Iwaisako, Keiko, Inokuchi, Sayaka, Schnabl, Bernd, Seki, Ekihiro, De Minicis, Samuele, Oesterreicher, Christoph, Taura, Kojiro
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Proceedings
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368775/
https://ncbi.nlm.nih.gov/pubmed/23259769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-5-S1-S17
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