Near-Infrared Fluorescence Imaging of Apoptotic Neuronal Cell Death in a Live Animal Model of Prion Disease

[Image: see text] Apoptotic cell death via activation of the caspase family of cysteine proteases is a common feature of many neurodegenerative diseases including Creutzfeldt−Jakob disease. Molecular imaging of cysteine protease activities at the preclinical stage may provide valuable mechanistic in...

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Hauptverfasser: Lawson, Victoria A., Haigh, Cathryn L., Roberts, Blaine, Kenche, Vijaya B., Klemm, Helen M. J., Masters, Colin L., Collins, Steven J., Barnham, Kevin J., Drew, Simon C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2010
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368636/
https://ncbi.nlm.nih.gov/pubmed/22778809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100068x
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