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Engineering a GPCR−Ligand Pair That Simulates the Activation of D(2L) by Dopamine
[Image: see text] In the past decade, engineered G-protein-coupled receptors activated solely by synthetic ligands (RASSLs) have been implemented as a new means to study neurotransmission, which is controlled by G-protein-coupled receptors in vitro and in vivo. In this study, we report an engineered...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368624/ https://ncbi.nlm.nih.gov/pubmed/22778805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn900001b |
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