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Engineering a GPCR−Ligand Pair That Simulates the Activation of D(2L) by Dopamine

[Image: see text] In the past decade, engineered G-protein-coupled receptors activated solely by synthetic ligands (RASSLs) have been implemented as a new means to study neurotransmission, which is controlled by G-protein-coupled receptors in vitro and in vivo. In this study, we report an engineered...

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Hlavní autoři: Tschammer, Nuska, Dörfler, Miriam, Hübner, Harald, Gmeiner, Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2009
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368624/
https://ncbi.nlm.nih.gov/pubmed/22778805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn900001b
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