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Increased EGFR Gene Copy Number Detected by Fluorescent In Situ Hybridization Predicts Outcome in Non–Small-Cell Lung Cancer Patients Treated With Cetuximab and Chemotherapy

PURPOSE: Epidermal growth factor receptor (EGFR) gene copy number detected by fluorescent in situ hybridization (FISH) has proven to be useful for selection of non–small-cell lung cancer (NSCLC) patients for treatment with EGFR tyrosine kinase inhibitors. Here, we evaluate EGFR FISH as a predictive...

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Библиографические подробности
Главные авторы: Hirsch, Fred R., Herbst, Roy S., Olsen, Christine, Chansky, Kari, Crowley, John, Kelly, Karen, Franklin, Wilbur A., Bunn, Paul A., Varella-Garcia, Marileila, Gandara, David R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368372/
https://ncbi.nlm.nih.gov/pubmed/18612151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2007.14.0111
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