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Human hypoblast formation is not dependent on FGF signalling

Mouse embryos segregate three different lineages during preimplantation development: trophoblast, epiblast and hypoblast. These differentiation processes are associated with restricted expression of key transcription factors (Cdx2, Oct4, Nanog and Gata6). The mechanisms of segregation have been exte...

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Autori principali: Roode, Mila, Blair, Kathryn, Snell, Philip, Elder, Kay, Marchant, Sally, Smith, Austin, Nichols, Jennifer
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368271/
https://ncbi.nlm.nih.gov/pubmed/22079695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2011.10.030
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