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Suppression of Erk signalling promotes ground state pluripotency in the mouse embryo
Embryonic stem (ES) cells can be derived and propagated from multiple strains of mouse and rat through application of small-molecule inhibitors of the fibroblast growth factor (FGF)/Erk pathway and of glycogen synthase kinase 3. These conditions shield pluripotent cells from differentiation-inducing...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2739140/ https://ncbi.nlm.nih.gov/pubmed/19710168 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.038893 |
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