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Pluripotency in the Embryo and in Culture

Specific cells within the early mammalian embryo have the capacity to generate all somatic lineages plus the germline. This property of pluripotency is confined to the epiblast, a transient tissue that persists for only a few days. In vitro, however, pluripotency can be maintained indefinitely throu...

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Detalhes bibliográficos
Main Authors: Nichols, Jennifer, Smith, Austin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3405859/
https://ncbi.nlm.nih.gov/pubmed/22855723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a008128
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