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Targeting Sphingosine-1-Phosphate in Hematologic Malignancies

Sphingosine-1-phosphate (S1P) is a pleiotropic bioactive lipid mediator that regulates several processes important for hematologic cancer progression. S1P is generated by two sphingosine kinases, SphK1 and SphK2, and is exported outside the cell, where it activates specific cell surface S1P G-protei...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Stevenson, Christina E., Takabe, Kazuaki, Nagahashi, Masayuki, Milstien, Sheldon, Spiegel, Sarah
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368248/
https://ncbi.nlm.nih.gov/pubmed/21707492
Tagiau: Ychwanegu Tag
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