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Pore Helix-S6 Interactions Are Critical in Governing Current Amplitudes of KCNQ3 K(+) Channels

Two mechanisms have been postulated to underlie KCNQ3 homomeric current amplitudes, which are small compared with those of KCNQ4 homomers and KCNQ2/Q3 heteromers. The first involves differential channel expression governed by the D-helix within the C-terminus. The second suggests similar channel sur...

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Autori principali: Choveau, Frank S., Bierbower, Sonya M., Shapiro, Mark S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368123/
https://ncbi.nlm.nih.gov/pubmed/22713565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.019
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