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Age-related Defects in TLR2 Signaling Diminish the Cytokine Response by Alveolar Macrophages during Murine Pneumococcal Pneumonia
Alveolar macrophages (AMs) are the first immune cells to respond to an invading pathogen and coordinate the inflammatory response within the lungs. Studies suggest that macrophages exhibit age-related deficiencies in Toll-like receptor (TLR) function; however, the impact of this dysfunction during p...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368096/ https://ncbi.nlm.nih.gov/pubmed/22548913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exger.2012.04.004 |
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