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Diminished adhesion and activation of platelets and neutrophils with CD47-functionalized blood contacting surfaces
CD47 is a ubiquitously expressed transmembrane protein that, through signaling mechanisms mediated by signal regulatory protein alpha (SIRPα1), functions as a biological marker of ‘self-recognition’. We showed previously that inflammatory cell attachment to polymeric surfaces is inhibited by the att...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368088/ https://ncbi.nlm.nih.gov/pubmed/22613135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.04.051 |
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