The effect of CD47 modified polymer surfaces on inflammatory cell attachment and activation

CD47 is a transmembrane protein that is a marker of “self”. CD47 binding to its cognate receptor in leukocytes and macrophages, signal regulatory protein alpha (SIRPα), causes inhibition of inflammatory cell attachment. We hypothesized that immobilization of recombinant CD47 on polymeric surfaces wo...

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Bibliografiske detaljer
Main Authors: Stachelek, Stanley J., Finley, Matthew J., Alferiev, Ivan S., Wang, Fengxiang, Tsai, Richard, Eckells, Edward C., Tomczyk, Nancy, Connolly, Jeanne M., Discher, Dennis E., Eckmann, David M., Levy, Robert J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108143/
https://ncbi.nlm.nih.gov/pubmed/21429575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.02.053
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