The effect of CD47 modified polymer surfaces on inflammatory cell attachment and activation

CD47 is a transmembrane protein that is a marker of “self”. CD47 binding to its cognate receptor in leukocytes and macrophages, signal regulatory protein alpha (SIRPα), causes inhibition of inflammatory cell attachment. We hypothesized that immobilization of recombinant CD47 on polymeric surfaces wo...

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Autores principales: Stachelek, Stanley J., Finley, Matthew J., Alferiev, Ivan S., Wang, Fengxiang, Tsai, Richard, Eckells, Edward C., Tomczyk, Nancy, Connolly, Jeanne M., Discher, Dennis E., Eckmann, David M., Levy, Robert J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3108143/
https://ncbi.nlm.nih.gov/pubmed/21429575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.02.053
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