Diminished adhesion and activation of platelets and neutrophils with CD47-functionalized blood contacting surfaces

CD47 is a ubiquitously expressed transmembrane protein that, through signaling mechanisms mediated by signal regulatory protein alpha (SIRPα1), functions as a biological marker of ‘self-recognition’. We showed previously that inflammatory cell attachment to polymeric surfaces is inhibited by the att...

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Bibliografiske detaljer
Main Authors: Finley, Matthew J., Rauova, Lubica, Alferiev, Ivan S., Weisel, John W., Levy, Robert J., Stachelek, Stanley J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368088/
https://ncbi.nlm.nih.gov/pubmed/22613135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.04.051
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