VANGL2 regulates membrane trafficking of MMP14 to control cell polarity and migration

Planar cell polarity (PCP) describes the polarized orientation of cells within the plane of a tissue. Unlike epithelial PCP, the mechanisms underlying PCP signaling in migrating cells remain undefined. Here, the establishment of PCP must be coordinated with dynamic changes in cell adhesion and extra...

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Bibliographic Details
Main Authors: Williams, B. Blairanne, Cantrell, V. Ashley, Mundell, Nathan A., Bennett, Andrea C., Quick, Rachel E., Jessen, Jason R.
Format: Artigo
Language:Inglês
Published: Company of Biologists 2012
Subjects:
Short Reports
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367937/
https://ncbi.nlm.nih.gov/pubmed/22357946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.097964
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