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Covalent Protein Modification with ISG15 via a Conserved Cysteine in the Hinge Region
The ubiquitin-like protein ISG15 (interferon-stimulated gene of 15 kDa) is strongly induced by type I interferons and displays antiviral activity. As other ubiquitin-like proteins (Ubls), ISG15 is post-translationally conjugated to substrate proteins by an isopeptide bond between the C-terminal glyc...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367918/ https://ncbi.nlm.nih.gov/pubmed/22693631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038294 |
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