PU.1 is linking the glycolytic enzyme HK3 in neutrophil differentiation and survival of APL cells

The transcription factor PU.1 is a master regulator of myeloid differentiation and function. On the other hand, only scarce information is available on PU.1-regulated genes involved in cell survival. We now identified the glycolytic enzyme hexokinase 3 (HK3), a gene with cytoprotective functions, as...

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Bibliografiset tiedot
Päätekijät: Federzoni, Elena A., Valk, Peter J. M., Torbett, Bruce E., Haferlach, Torsten, Löwenberg, Bob, Fey, Martin F., Tschan, Mario P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Hematology 2012
Aiheet:
Myeloid Neoplasia
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367898/
https://ncbi.nlm.nih.gov/pubmed/22498738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-09-378117
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