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Bioinformatics and variability in drug response: a protein structural perspective
Marketed drugs frequently perform worse in clinical practice than in the clinical trials on which their approval is based. Many therapeutic compounds are ineffective for a large subpopulation of patients to whom they are prescribed; worse, a significant fraction of patients experience adverse effect...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Royal Society
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367825/ https://ncbi.nlm.nih.gov/pubmed/22552919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0843 |
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