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Bioinformatics and variability in drug response: a protein structural perspective

Marketed drugs frequently perform worse in clinical practice than in the clinical trials on which their approval is based. Many therapeutic compounds are ineffective for a large subpopulation of patients to whom they are prescribed; worse, a significant fraction of patients experience adverse effect...

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מידע ביבליוגרפי
Main Authors: Lahti, Jennifer L., Tang, Grace W., Capriotti, Emidio, Liu, Tianyun, Altman, Russ B.
פורמט: Artigo
שפה:Inglês
יצא לאור: The Royal Society 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367825/
https://ncbi.nlm.nih.gov/pubmed/22552919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0843
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