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Bioinformatics and variability in drug response: a protein structural perspective
Marketed drugs frequently perform worse in clinical practice than in the clinical trials on which their approval is based. Many therapeutic compounds are ineffective for a large subpopulation of patients to whom they are prescribed; worse, a significant fraction of patients experience adverse effect...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Royal Society
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367825/ https://ncbi.nlm.nih.gov/pubmed/22552919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsif.2011.0843 |
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