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Interactions between the C-terminus of Kv1.5 and Kvβ regulate pyridine nucleotide-dependent changes in channel gating

Voltage-gated potassium (Kv) channels are tetrameric assemblies of transmembrane Kv proteins with cytosolic N- and C-termini. The N-terminal domain of Kv1 proteins binds to β-subunits, but the role of the C-terminus is less clear. Therefore, we studied the role of the C-terminus in regulating Kv1.5...

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Hlavní autoři: Tipparaju, Srinivas M., Li, Xiao-Ping, Kilfoil, Peter J., Xue, Bin, Uversky, Vladimir N., Bhatnagar, Aruni, Barski, Oleg A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367765/
https://ncbi.nlm.nih.gov/pubmed/22426702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-012-1093-z
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