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Catalytic mechanism and substrate specificity of the β-subunit of the voltage-gated potassium (Kv) channel

The β-subunits of voltage-gated potassium (Kv) channels are members of aldo-keto reductase (AKR) superfamily. These proteins regulate inactivation and membrane localization of Kv1 and Kv4 channels. The Kvβ proteins bind to pyridine nucleotides with high affinity; however, their catalytic properties...

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Detalhes bibliográficos
Main Authors: Tipparaju, Srinivas M., Barski, Oleg A., Srivastava, Sanjay, Bhatnagar, Aruni
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2603305/
https://ncbi.nlm.nih.gov/pubmed/18672894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800301b
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