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Selective tumor killing based on specific DNA-damage response deficiencies

Organisms constantly undergo various stresses within their life span, which can damage their DNA. In order to maintain genomic stability and counteract the development of unwanted genomic mutations, organisms have evolved a DNA-damage response (DDR) to protect their genome. Due to the critical roles...

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Autors principals: Biss, Michael, Xiao, Wei
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367714/
https://ncbi.nlm.nih.gov/pubmed/22258411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.13.5.18921
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