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Selective tumor killing based on specific DNA-damage response deficiencies
Organisms constantly undergo various stresses within their life span, which can damage their DNA. In order to maintain genomic stability and counteract the development of unwanted genomic mutations, organisms have evolved a DNA-damage response (DDR) to protect their genome. Due to the critical roles...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Landes Bioscience
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367714/ https://ncbi.nlm.nih.gov/pubmed/22258411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.13.5.18921 |
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